Van de Ven Brace Halts The Toffees' Unbeaten Streak at Brand New Stadium
The Dutch defender became the first defender to net twice in a Premier League match for Tottenham since the Belgian defender in spring 2013.
At a glance
The Spurs defender nods home twice in first half
Everton's Jake O'Brien has goal ruled after video check
Senegalese midfielder nets third in 89th minute
The defeat is Everton's initial at their new ground
Micky van de Ven found the net on two occasions as Spurs extended their unbeaten run on the road in the Premier League and handed Everton their first defeat at their new home.
Everton were unbeaten in their five previous fixtures at their new ground at the dockside location, having left Goodison Park behind after more than a century at the end of last season.
But Spurs captain Van de Ven pounced twice from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were failed to turn it around before Pape Matar Sarr - assisted by former Toffees attacker Richarlison - nodded in a third to put the game to bed.
Jake O'Brien thought he had equalized the scores five minutes after the defender's opener, directing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, meanwhile, missed a number of opportunities, while the Italian goalkeeper made a series of excellent stops to guarantee Tottenham went five matches on the road without defeat in the Premier League.
But the video assistant referee stepped in, instructing the match official to review the goal on the pitchside monitor and the referee decided that the winger and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory moves Thomas Frank's side up to third in the division, a handful of points off north London rivals and table-toppers the Gunners.
Everton stay in 14th position and sit six points ahead of the drop zone.
Tottenham analysis: The defender excels in role at each end of pitch
After a uninspiring weekday performance in the European competition against the French side, where they managed a mere two shots on goal, Frank chose Randal Kolo Muani in attack instead of former Toffees player the Brazilian.
The new arrival was unable to influence the game before being substituted for the substitute after an hour on the pitch, but it emerged he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an attacking force to be reckoned with.
Spurs' first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an unmarked the defender to head home.
And Ven de Ven - filling in as captain in Cristian Romero's unavailability - notched his next goal in added time as he outjumped Jordan Pickford to head home.
Van de Ven was equally outstanding in defence, partnering well with his defensive colleague as the pair dealt excellently with the numerous deliveries thrown their way by the opposition.
Everton analysis: Everton missing striker's instinct
The club's recent stadium had been a fortress, but it seems the novelty may have worn off slightly and supporters flocked to the gates after Sarr's final goal for Tottenham.
The end in the team's winning streak at home won't be a massive concern for the manager, but their striker situation will be.
The forward and the other striker - the Everton's two established centre-forwards - had netted just one league goal combined before Sunday's outing.
And they were unable to contribute to that poor record on a damp and dreary night on Merseyside.
Beto's performance was epitomized when he opted to overhead kick a clear chance from near the goal, despite having space and time to reposition for a more conventional shot that would have challenged Vicario.
The substitute, as well, failed to make an impact after replacing the starter in the second half.
It was not for a shortage of opportunity. The majority of Everton's offensive moves came through the winger and the forward, who relentlessly whipped threatening crosses into the Spurs penalty area.
What next for these two sides?
Everton: Moyes' men travel to Sunderland in the Premier League on early November at 8 PM.
Spurs: Spurs go to St James' Park on late October for their next round League Cup match against Newcastle.